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10.1080/14786419.2016.1272108 134 LiX.WuK.ZengS.ZhaoF.FanJ.LiZ.et al (2021)

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Shipping delays, payment processing holds, or supplier stock issues can create 35 day gaps, and even a single missed injection disrupts steady-state antioxidant activity

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[] Free radicals damage the RBC products by lipid, protein oxidation and oxidative loss with changes in the structure of the RBCs membrane leads to an increase in the accumulation of band-3 protein, lipid oxidation and apoptotic changes in the last weeks of storage