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Patients with HFrEF and concomitant T2D show consistently lower Kansas City Cardiomyopathy Questionnaire (KCCQ) scores than those without T2D

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C: CHIR99021, 14 mg/kg

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The peptide N-terminus is highly conserved between GLP-1, exendin-4 and oxyntomodulin, and as such, a large number of receptor contacts are also conserved, whereas these are more divergent when compared with exendin-P5 (Supplemental Table 1)

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