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BH4 is a strong antioxidant that sequesters radicals and, either by itself or in combination with vitamin E, prevents lipid membranes from undergoing autoxidation (189).The transsulfuration pathway, mevalonate pathway, ferroptosis inhibitory protein 1 (FSP1)-coenzyme Q10 (CoQ10) pathway, dihydroorotate dehydrogenase (DHODH)-dihydroubiquione (CoQH2) pathway, and GTP cyclohydrolase-1 (GCH1)-tetrahydrobiopterin (BH4) pathway are among the other antioxidant systems that have also been linked to the regulation of ferroptosis (190) ( Figure 5 )
Glutathione is considered the master antioxidant of the human body
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Anti-Aging Effects Integration The anti-aging benefits of growth hormone optimization integrate into a cohesive improvement in biological age markers
doi: 10.7759/cureus.23494 42
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