Substantial contributions to the conception or design of the work
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Some previous studies have found associations between semaglutide and suicidal thoughts
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10.1016/s0006-8993(01)03067-0 Summary Keywords GLP-1, exenatide, microdialysis, dopamine, nucleus accumbens Citation Edvardsson CE, Vestlund J, Ericson M and Jerlhag E (2024) The GLP-1 receptor agonist exendin-4 reduces taurine and glycine in nucleus accumbens of male rats, an effect tentatively involving the nucleus tractus solitarius
The treatment attenuated VPA-induced behavioral abnormalities in both Y-maze and social play tests, while also restoring prefrontal SOD and GSH-Px activity and normalizing VPA-related changes in neuronal number and soma size (Margedari et al., 2024)