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Four LPCAT isoforms are known to date, among which LPCAT3 is able to preferentially catalyze the reversible exchange of fatty acids between the sn-2 position of lysophosphatidylcholine and the acyl-CoA pool, thereby increasing long-chain PUFAs to engage in the synthesis of membrane phospholipids (32)

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Whether this approach may be suited to counteract these disabilities in multiple sclerosis patients, remains to be further determined

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