If your doctor is hesitant to prescribe a GLP-1, ask about other weight management options, including: Metabolic testing to assess how your body processes food and determine if underlying issues are affecting weight loss
We began exploring different routes of administration, initially focused on insulin and GLP-1
Lilly is studying retatrutide in several Phase 3 clinical trials to evaluate its potential efficacy and safety in obesity and overweight with at least one weight-related medical problem, type 2 diabetes, knee osteoarthritis pain, moderate-to-severe OSA, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatotic liver disease
While newer treatments like Retatrutide are generating excitement, established options like Tirzepatide remains the current standard
In the context of kidney stones, obesity increases urinary excretion of calcium, oxalate, and uric acid whilst decreasing urinary pH, creating conditions favourable for stone formation
Lynn AM, Harmsen WS, Tremaine WJ, Loftus EV