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Most new compounds that can potentially create new nerve connections and brain cells are compared to brain-derived neurotrophic factor (BDNF) because its most known for this

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A clinical proof-of-concept trial used 0.03 mg/kg twice daily for short durations and found the drug to be generally well tolerated, though efficacy endpoints were mixed depending on the indication

Weaker, extended mitogen-promoted signaling is associated with cell differentiation

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