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Overcoming Multidrug Resistance Using Liposomal Epirubicin and Antisense Oligonucleotides Targeting Pump and Nonpump Resistances In Vitro and In Vivo

However, clinical outcomes remain inconsistent, largely due to variability in dosing strategies, treatment length, and individual patient responsiveness

MAPK, Mitogen-Activated Protein Kinase

In patients with alcohol dependence and delirium unresponsive to high doses of benzodiazepines, alcoholic pellagra should be considered, since chronic alcoholism leads to a lack of tryptophan 2,3-dioxygenase, an enzyme linked to niacin synthesis

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In brief, samples were diluted in the provided assay buffer and added to the wells of a half-area clear plate