Having optimal levels in blood and tissues helps to prevent disorders of the central nervous system, mood disorders, and vascular and Alzheimers dementia later in life
However, it is imperative to understand that fragment 176-191 (AOD-9604) does not have any effect on the level of insulin or insulin resistance
Gastrointestinal effects are the most frequently reported side effects and include: Nausea (1224% of patients): Often most pronounced during treatment initiation and dose escalation, typically improving over time Diarrhea (1323% of patients): May be transient or persistent, requiring dietary modifications Vomiting (611% of patients): Can lead to dehydration if severe or prolonged Constipation (617% of patients): May require increased fiber intake and hydration Abdominal pain or discomfort (610% of patients): Usually mild to moderate in severity Decreased appetite : Therapeutic effect but may be excessive in some individuals These gastrointestinal symptoms generally diminish over several weeks as the body adjusts to the medication
Methylcobalamin Cyanocobalamin : Synthetic, contains a cyanide molecule, requires liver conversion before use
Duzel A, Vlainic J, Antunovic M, Malekinusic D, Vrdoljak B, Samara M, et al
Your body doesnt make B12 on its own