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Th e incidence of true penicillin allergy (a type I reaction which is immunoglobulin E [IgE] mediated) is 15 years) is associated with only a very low risk (0.4%) of reactions [20] , and only 2030% of patients positive on a penicillin skin test remain positive after ten years [21]

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All testing solutions were prepared by diluting stock solution with DMSO and PBS/imaging buffer/culture medium