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Doxycycline inhibits TGF-beta1-induced MMP-9 via Smad and MAPK pathways in human corneal epithelial cells

Without understanding the pathophysiologic basis for these diseases, developing effective treatments will remain challenging

How do antimicrobial peptides disrupt the lipopolysaccharide membrane leaflet of Gram-negative bacteria

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This dose falls within the effective clinical range while allowing room to increase if response is minimal

Beyond lipids, pharmacological PPARa activation has important effects on amino acid metabolism as studied in the rat