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It should not be used as a drug or injection, since the FDA has not approved it for human use

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Cagrilintide, the second generation (2020s) Novo Nordisk took the Pramlintide concept and applied the same half-life extension strategy that they used with Semaglutide: Kept the proline substitutions (anti-amyloid) Added a C20 fatty diacid via a -Glu linker to a lysine residue, albumin binding Additionally stabilized the N- and C-terminal positions Result: Cagrilintide with a half-life of 6.6 days (vs 50 minutes for Pramlintide)

also reported that SRS concurrent with monoclonal antibodies improved ILC (1-year LF: 10.2% vs 18.4%, P = 0.003) (126)

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