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It is believed that these effects may be associated with immune hyperactivation in the central nervous system (CNS) (68), along with endocrine disturbances such as hypophysitis (69)

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Although these discrepancies may be because of the different techniques used to measure the receptor protein, namely autoradiography vs immunohistochemistry, they may also be related to the antibodies used and their level of characterization and validation, as mentioned by Drucker 11 and Pyke et al

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