Krakauer JC, McKenna MJ, Buderer NF, Rao DS, Whitehouse FW, Parfitt AM
Apr 2006(134):1-161
Apply sunscreen during the day to protect your skin from sun damage
There are several drug candidates that are in later stage clinical trials which includes PPAR agonists, anti-fibrotic therapies, anti-inflammatory agents, antioxidants, and treatments targeting the gut-liver axis (154)
For best results, take 1-2 tablets daily, preferably before workouts or as directed by a healthcare professional
Common mechanisms include enhancing antioxidant defenses (typically through activation of the Nrf2/ARE pathway), inhibiting pro-inflammatory signaling (e.g., NF-B and MAPK pathways), increasing nitric oxide (NO) bioavailability in endothelial cells, regulating lipid metabolism, and alleviating pathological fibrosis