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Dysregulation of the bloodbrain barrier increases permeability and contributes to pathologies, including Alzheimer's disease, epilepsy, and ischemia

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Moreover, AA patients exhibit elevated blood levels of malondialdehyde (a lipid peroxidation product), potentially causing disorders in cysteine metabolism and heightening the risk of ferroptosis (Cwynar et al

Failures in mitophagy are associated with several chronic diseases, including cardiovascular disease, kidney disease, and Alzheimers disease

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