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Deamidation rates increase with temperature and also depend on pH and the sequence of neighboring amino acids
A Phase III, Randomised, Double Blind, Placebo Controlled, Parallel Group Study, to Evaluate the Safety and Efficacy of Subcutaneous Implants of Afamelanotide (16 mg) in Patients Suffering From Polymorphic Light Eruption (PLE) (Report)
These were averaged to generate a single data point (Fig
Many patients wonder if taking their injection a day or two early disrupts the therapeutic effect or creates safety concerns
The patient had no history of drug abuse, anticoagulation or trauma
Because about 90% of oral L-carnitine supplements is unlikely to be absorbed, one could ask whether the efficacy is equivalent between protocols using both intravenous and oral administration and those using oral administration only (8)
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