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Research models focus on pathway convergence signalling sequencing and molecular cooperation between cytoprotective and structural regulatory systems

In the second reaction, the active site cysteine reduction and regeneration of OsDHAR is initiated by binding of the first GSH molecule at the G-site followed by the second GSH binding at the H-site

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Introduction The first reports about a plant glutathione S-transferase enzyme (GST, EC 2.5.1.18) appeared in 1970, when it was revealed that a GST catalyzed the detoxification of the herbicide atrazine by its conjugation to the endogenous tripeptide glutathione (GSH, -L-glutamyl-L-cysteinyl-glycine) in sorghum and maize plants (Frear and Swanson, 1970)