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A personal or family history of medullary thyroid cancer, MEN 2, a history of pancreatitis, or severe GI disease may rule these out or require caution

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Among the twelve peptides removed from the Category 2 list (effective April 23, 2026): Removal from Category 2 is separate from the FDAs review of which peptides may be compounded under section 503A

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That is one of the reasons, as the NICE guideline says, that we need to adjust treatment to the patients symptoms, not do a blood test or prescribe a one-size-fits-all dose