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Glucagon-like peptide 1 receptor agonist (GLP-1 RA): Long-term effect on kidney function in patients with type 2 diabetes

Diab Investig

What do they do

Food And Drug Administration, September 30, 2021, Office of the Commissioner

Stomach As food reaches the stomach, acid activates pepsin, a protein-digesting enzyme (protease) and the bodys first major player in breaking down dietary protein.15 Pepsin cuts large proteins into smaller fragments called peptides

However, the recommendation also stresses close monitoring, gradual reductions in insulin doses, maintaining adequate carbohydrate intake, ketone testing, sick-day rules and careful dose titration [4]