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Among lymphocytes, CD8 + T cells are particularly sensitive to cholesterol depletion, as low cholesterol levels hinder their proliferation and induce autophagy-mediated apoptosis

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doi: 10.3389/fonc.2022.917634 Received 11 April 2022 Accepted 13 May 2022 Published 27 June 2022 Volume 12 - 2022 Edited by Eduard Yakubov, Paracelsus Medical Private University, Germany Reviewed by Aayushi Mahajan, Columbia University, United States

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These results confirm and extend the finding in STZ diabetic rats [95], suggesting that dietary non-iron supplements may partially prevent the development of peripheral diabetic neuropathy (PDN) [96]

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