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This condition happens when there is excess melanin, which is the pigment that is responsible for skin color

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In studies, subjects are able to perform more repetitions and experience less post-exercise muscle soreness when supplementing with citrulline malate

Finally, individuals with compromised liver or kidney function, or those with severe gastrointestinal diseases like Crohn's or ulcerative colitis, require highly modified protocols

S., Brcic, L., et al