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This most often entails Abs of the IgG1 and IgG3 subclasses, which are both potent in activating the immune system through activation of the complement cascade and eventual formation of the membrane attack complex [137, 145], targeting the acetylcholine receptor (AChR)

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To further verify the effects on mitochondria, we checked the effects of MMP (represents mitochondrial function) by TMRM staining in atorvastatin-supplemented HCM and C2C12 cells