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Dose titration and administration : According to the Ozempic SmPC, treatment is initiated at 0.25 mg once weekly for four weeks, then increased to 0.5 mg weekly

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The published protocol uses a stepwise escalating-amount schedule, with participants starting at 2.5 mg weekly and increasing in 2.5 mg increments at 4-week intervals until the target maintenance amount is reached, in order to mitigate gastrointestinal adverse events characteristic of incretin-class agents

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Adiposity and cancer: meta-analysis, mechanisms, and future perspectives