gip/glp-1 The dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide: a novel cardiometabolic therapeutic prospect | Cardiovascular Diabetology Dual GLP-1/GIP Agonist | Tirzepatide

They can also help type 1 diabetes patients lose weight, something thats especially difficult for people who take insulin, which signals the body to take extra sugar out of the blood and store it as fat

Animals were housed under a 12 h light/dark cycle at a room temperature of 22 1 C with 45% humidity, given ad libitum access to food and water

GLP-1 signaling in pancreatic -cells increases insulin secretion in a blood glucose level-dependent manner, leading to decrease of blood glucose levels 3

How to keep the weight off after GLP-1s If you plan to stop taking a GLP-1 medication, you should create a plan to prevent potential weight regain

Further competition comes from tirzepatide, approved by the FDA in 2022 and now sold under the Mounjaro/Zepbound brand name

Earlier this year, animal research published in eBioMedicine (February 2026) added to a growing body of evidence suggesting that medications acting on the GLP-1 system may one day play a role in treating alcohol use disorder ( AUD )