The mechanism proposed by the originators is a peptideDNA / tissue-specific gene-expression effect: short bioregulator peptides are hypothesized to interact with chromatin and modulate gene expression in a target tissue
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Since \( f''(x) \) does not change sign at \( x = 0 \), it follows that \( x = 0 \) is not an inflection point
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Oxidation of malate, catalyzed by malate dehydrogenase, finally regenerates oxaloacetate, and the cycle continues