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Hormonal changes during perimenopause and menopause influence insulin sensitivity, appetite regulation, and medication tolerance

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Glucagon-like peptide-1 receptor agonists (GLP-1) drugs offer an extremely effective option for many to lose weight but their effects on health dont stop there

This can lead to sarcopenia, reduced metabolic rate, and aesthetic concerns like sagging skin

Avoid prolonged exposure to very cold environments if possible, and stay well-hydrated, as dehydration can amplify the sensation of being cold

Digital z-stacks were collected with a Zeiss LSM 880 confocal microscope (20x and 63x)