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They developed a method to find these substances in urine

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Concomitant Medications Advise patients to notify their physicians if they are taking, or plan to take, any prescription or over-the-counter drugs because there is a potential for interactions [see Drug Interactions (7.1)]

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Obesity is defined as having a BMI of 30 kg/m2 or above and is linked to an increased risk of developing chronic illnesses