Stanton-Fay SH, Hamilton K, Chadwick PM, Lorencatto F, Gianfrancesco C, de Zoysa N, et al
Fisetin has been shown to reduce nitric oxide (NO) and prostaglandin E production by inhibiting the inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and IL-1 pathways (23)
These have properties to reduce oxidative stress by increasing superoxide dismutase (SOD) and decreasing serum malondialdehyde (MDA)
It has been associated with several other potential health benefits, including reducing the risk of chronic diseases, such as cardiovascular disease, age-related macular degeneration and certain types of cancer, and may also have anti-inflammatory properties that play a role in supporting brain health
Sequential measurements were made of muscle strength (one repetition maximum), body composition (dual energy x-ray absorptiometry), and circulating levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3
Shukla SD, Hanahan DJ
