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doi: 10.31491/apt.2023.03.109 [DOI] [PMC free article] [PubMed] [Google Scholar] Sakuma Satoru et al

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Similar content being viewed by others Introduction Anxiety and depression have become the leading mental health challenges worldwide, affecting millions of people each year, with a substantial increase following the COVID-19 pandemic [1]

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Results Robustly increased longevity in GHRH-KO mice To investigate the effect of isolated GH deficiency on lifespan, we evaluated differences in longevity of GHRH-KO (KO) mice and littermate (wild-type) control mice on ad libitum (AL) standard diet

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are naturally occurring hormones that regulate appetite, insulin secretion, and metabolism