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IGF-1 LR3's dramatically reduced IGFBP affinity means it remains predominantly in the free, receptor-active form, producing a much greater effective concentration at the IGF-1R for any given total protein amount added to an experimental system

10.1016/j.plaphy.2010.08.016 45 GomathiR.RakkiyapanP

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Las venas dilatadas visibles a ojo desnudo con los nuevos medios de iluminacin y de refleccin y absorbimiento a nuestra disposicin as como las telangiectasias capilares, son inyectadas con la solucin regenerativa, y el lquido que se difunde ms facilmente en los vasos ms dilatados va a realizar su accin teraputica en el endotelio de las venas perforantes no visibles, perforantes que representan la causa ms frecuente de la enfermedad varicosa

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For BPC-157, the mechanistic story is interesting