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Plasma concentrations of GHK-Cu are high in youth (~200ng/mL at age 20) and decline significantly with age (~80ng/mL by age 60) a pattern that has made it a focal compound in longevity and regenerative biology research
Within the class S4 of hormone and metabolic modulators of the WADA Prohibited List, 39% of the adverse analytical findings (AAF) reported in 2020 resulted from SERMs (tamoxifen and clomiphene) and another 29% from AIs (letrozole, anastrozole, exemestane, and adrostatrienedione) (World Anti-Doping Agency, 2022)
doi:10.1038/s41572-025-00603-8
Biomedicines 10 (10), 2380
It may also increase growth factors, which are necessary for any tissue repair
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