Metformin Action: Concentration Matters
The drugs are already showing early promise in treating alcohol and opioid addictions due to their ability to ease cravings a symptom found across addictions
Yet, to delineate their immunomodulatory potential distinct from metabolic effects, rigorous, randomized controlled trials in metabolically healthy dermatologic populations are essential
Mostly not approved, and the safety data is limited
Compared to HCs, 103 metabolites were elevated but 123 were declined in the R group ( Figure 2F )
Acknowledgements This work was supported by the National Natural Science Foundation of China (82374290), Excellent Young Science and Technology Talent Cultivation Special Project of Chinese Academy of Chinese Medical Sciences (CI2023D006) and The Young Qihuang Scholar of the Tens of Millions Talent Project of China (Yue Liu)