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Consistent with DOG box enrichment, all GS-like genes from Clade 3 analysed by in situ hybridisation were highly and specifically expressed in the secretory dorsal gland cells in a range of parasitic stage nematodes (Fig 2A and S3 Fig), while Clade 1 and Clade 2 GS-like genes were expressed in both female and male nematodes, with often preferential expression in the intestine (Fig 2A and S3 Fig
Although that doesnt mean the results to generalize to patients without HIV or who arent on antiretroviral therapies
These medicines have undergone rigorous clinical evaluation, have approved SmPCs, and are prescribed with appropriate monitoring and follow-up
It acts as a primary internal defense system
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