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For patients with diabetes and MASLD, SGLT2 inhibitors may offer metabolic and cardiovascular benefits while potentially improving liver health

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In June 2025, the European Medicines Agency officially recognized NAION as a very rare side effect of semaglutide after reviewing all data, concluding it may affect up to 1 in 10,000 people and recommending product information updates

Furthermore, tirzepatide demonstrates enhanced affinity for GLP-1R relative to native GLP-1, while simultaneously engaging the GIP receptor, thereby amplifying its therapeutic efficacy in glycemic control and weight reduction (Fig

Each weight management plan begins with a medical consultation to evaluate eligibility for GLP-1 injections or other weight loss programs

For its part, Lilly would likely be able to bring Lanham Act cases against a similarly broad array of actors