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It helps regulate blood sugar by stimulating insulin release

Insulin resistance is a key driver of fatty liver disease

A new clinical trial, co-led by endocrinologist and diabetes expert John Buse, MD, PhD, and interventional cardiologist Matthew Cavender, MD, MPH, at the UNC School of Medicine has shown that the oral form of semaglutide can significantly reduce cardiovascular events in people with type 2 diabetes and atherosclerotic cardiovascular disease, and/or chronic kidney disease

Initial concerns about the relationship between GLP-1 receptor agonists and pancreatitis emerged from early preclinical studies and post-marketing reports, which suggested an increased incidence of pancreatitis among users of this class of medications

Qsymia combines phentermine and topiramate (a seizure medication used off-label for appetite suppression)

doi: 10.1136/bmj.l4898