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Semaglutide-treated neurons also displayed autophagy restoration that was compromised by beta-amyloid treatment [66]

Lancet Diabetes Endocrinol 11(6):426440

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For example, circulating IGF-1 and IGF-2 bind to the IGF-1 receptor (IGF-1R) and trigger a signal transduction cascade that leads to increased proliferation and enhanced survival of IGF-responsive cells (Figure 1)