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FIGURE 4 Glutathione Peroxidase 1 Attenuates Peroxynitrite-Induced Oxidative Stress in Spiral Ganglion Neurons Glutathione peroxidase 1 is known as a major intracellular peroxide-scavenging enzyme to eliminate the damage of ROS to cells, proteins, and liposomes through the reduction of glutathione

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Interestingly, this NMDA receptor-mediated activity-dependent myelination requires the simultaneous presence of glutamate and growth factors like brain derived neurotrophic factor (BDNF), hinting at the importance of surrounding glial cells (Lundgaard et al., 2013)