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Lipoprotein apheresis reduces Lp(a) by 3070% but is invasive and costly
On the other hand, by producing SCFAs to reduce the pH, the microbiota can improve iron bioavailability in the colon [133]
Despite currently holding a smaller share, this steady increase has been paired with government support, with the most recent support consisting of a program where general practitioners receive monetary bonuses from the government for prescribing a GLP-1 treatment plan for weight loss patients
Important factors affecting GLP-1 market demand and take-up include: The need for better long-term data on the safety and efficacy of use for the designated indications The rapidly expanding list of potential new indications for the drugs, including chronic kidney disease, broader cardiovascular risk reduction, metabolic liver disease, and Alzheimer's disease The number of similar drugs in the development pipeline Price point versus competition, which affects affordability and insurance coverage Marketing efforts of the manufacturers, supply and distribution constraints
Liu R, Li X, Xiao W, Lam KS
