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The one supplement to use with caution is iodine, which makes the thyroid work more efficiently and make more thyroid hormones

Severe gastrointestinal symptoms during semaglutide treatment, including persistent nausea, vomiting, or diarrhea, warrant medical consultation, particularly in anticoagulated patients

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Smokers and Heavy Alcohol Consumers Smoking and heavy alcohol use can weaken the LES, making acid reflux worse