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This regulatory action marks the first official link between semaglutide use and NAION, reinforcing concerns raised by earlier studies and intensifying scrutiny of these popular GLP-1 receptor agonists in ongoing semaglutide lawsuits

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Nevertheless, it was noteworthy that the supplementation led to a reduction in CRP levels, suggesting a potential influence on systemic inflammation in this particular population (WMD: 5.51 mg/dL, 95% CI: 9.18 to 1.83, p = 0.003)