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Integrin 51FAK/Src signaling is activated by alteration in the ECM composition, which in turn enhances the motility, while lymphocyte infiltration is restricted by the dense collagen network, adding another layer of immunosuppression (113)

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Omega-3s Omega-3 fatty acids are found in many foods but are most common in fish, crustaceans (like krill), walnuts, and flaxseed

Dec 2016;11(4):525-529

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Adipose tissue produces hormones such as leptin and estrogen (through aromatization of androgens), both of which influence bone density