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The efficacy of ADS-5102 was assessed in two randomized trials, EASE LID and EASE LID 3, which included 121 and 75 patients, respectively

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1 L-carnitine has been shown in animal models to stabilize mitochondrial membranes, increase energy delivered to organelles, and protect against cellular apoptotic death

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Zhu et al., 2020)

Statistical significance can be achieved with small samples when effect sizes are large, but generalisability remains uncertain