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The concentration of serotonin can be modulated by the gut microbiome in multiple ways [230], most notably shown by altered concentration of serotonin and its metabolites in the hippocampus of germ-free animals [231]

The mean age of symptom onset was 36.117.7 years (range, 8~64 years), with 10 cases (55.5%) within the ages 20~49 years

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B Vitamins are essential for proper thyroid function and Vitamin D deficiency has also been associated with low thyroid

The pain can range from mild tingling to sharp, shooting sensations that make standing, sitting, or walking uncomfortable

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