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Twice-daily exenatide should be administered within 60 minutes before morning and evening meals for optimal post-meal glucose control

Liraglutide improves insulin sensitivity in high fat diet induced diabetic mice through multiple pathways

This is similar as our previous results in DIRKO mice, which have both GIP and GLP-1 receptor gene deletion ( The reason why GIP receptor KO mice had glucose intolerance at higher glucose levels seems to be explained by the failure to further increase insulin levels

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The author finds that MN technology has a significant potential as a substitute method of transdermal delivery, but additional clinical and regulatory standardization is needed to achieve the goal of integrating MNs into therapeutic use [159]