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In the ELIXA trial, lixisenatide ameliorated macroalbuminuria assessed as a decline in the urinary albumin-to-creatinine ratio
These reflect either elevated cardiometabolic risk (prediabetes) or established cardiovascular disease (prior heart attack, prior stroke, symptomatic PAD)
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PMID: 29 AtzeniFGerratanaEFrancesco MasalaIBongiovanniSSarzi-PuttiniPRodrguez-CarrioJ
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