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The oversupply of energy induces injury of mitochondria and causes a potential toxic conditions of cells (Picard and Turnbull, 2013)

However, it is important to note that scRNA-seq has limited sensitivity for detecting lowly expressed genes, which may lead to an underestimation of the presence or variability of certain channels and receptors in the dataset [44]

The production of intrinsic factor happens in the stomach, which if impaired, can have a hard time properly synthesizing this protein

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