& Stephens, J
GLP-1s also reduce your appetite, so you end up eating less
doi:10.1056/nejmoa1411892 Davies MJ, Bergenstal R, Bode B, Kushner RF, Lewin A, Skjth TV, et al
When excluding TZP from the dataset, the overall efficacy of GLP-1RAs was reduced significantly and resulted in a slight body weight loss (-2.40 kg, 95% CI -3.04
The rising appeal of GLP-1 drugs for cosmetic weight loss has led to a significant increase in off-label prescribing, which can result in the potential for unnecessary claims, legal or ethical dilemmas and the risk of poor health outcomes for individuals who may not receive the right support for their condition
Animal reproduction studies have shown fetal harm, including structural abnormalities and growth alterations, though human data remain limited