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Some protocols combine approaches, using local injection near primary wounds with periodic systemic dosing for comprehensive support

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Active cGAS-STING signaling has also been linked with the production of certain chemokines that recruit T cells to the tumor site such as CXCL10, as well as induction of T-cell stemness (197, 215)

The specific doses in the published research focused on demonstrating proof of concept rather than establishing detailed dose-response curves

They met with members of Congress and attended industry conferences, walking legislators and their staffs through how 503A and 503B pharmacies actually work

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