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All these data are shown in Figures 2, 3, and Figure 5

The effect of increasing intestinal short-chain fatty acid concentration on gut permeability and liver injury in the context of liver disease: A systematic review

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Enteroendocrine cells within the mucosal lining of the gut synthesize and secrete a number of hormones including CCK, PYY, GLP-1, GIP, and 5-HT, which have regulatory roles in key metabolic processes such as insulin sensitivity, glucose tolerance, fat storage, and appetite

10.1038/s41572-019-0118-8 8 ChenC

The average weight loss from the drug in one trial was ~8.4kg