A structural explanation for these findings was provided from our previous cryo-EM structures of CT(Pro32) and rAmy(Tyr37)-bound AMYRs structures where the bulky phenolic side chain of Y37 rAmy forms perpendicular stacking interactions with W79 ECD 15 , and additional interactions with the respective RAMP protomer that are likely important for selectivity of rAmy for AMYRs over CTR
PMID: 11146367 Ng, F.M., et al
It may help with post-workout soreness, joint stiffness, and general inflammation, as well as assist the bodys natural healing response to injuries or overuse
Sensory needs dont exist in isolation
Rather than acting through a single receptor or signalling pathway, published research suggests that GHK-Cu can influence numerous genes involved in tissue remodelling, inflammatory responses, antioxidant defence and cellular repair
Understanding the pharmacology shapes the dosage logic